Organisateurs
Mont Ste Odile (France)
 14 - 17 Octobre   2020

45ÈME SYMPOSIUM SUR LES HORMONES ET LA RÉGULATION CELLULAIRE

Sex and Signaling: the molecular basis of sex and gender medicine

Symposium européen sur les hormones et la régulation cellulaire
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45ÈME SYMPOSIUM SUR LES HORMONES ET LA RÉGULATION CELLULAIRE

EUROPEAN SOCIETY OF ENDOCRINOLOGY (ESE)   
Sex and Signaling: the molecular basis of sex and gender medicine
Ilpo Huhtaniemi (Finland/UK)
Adriana Maggi (Italy)
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Comité scientifique :
Jacques E. Dumont, President (Belgium) 
David Carling (UK) 
Pierre De Meyts (Belgium) 
Veit Flockerzi (Germany) 
Ilpo Huhtaniemi (UK and Finland) 
Adriana Maggi (Italy) 
Bernard Payrastre (France)
Jean-Philippe Pin (France) 
Stephane Schurmans (Belgium) 
Maria Sibilia (Austria)   

Représentants ESE
Alex Harrison (UK) 
Bulent Yildiz (Turkey)

IN MEMORIAM : JACQUES NUNEZ

Nunez a major contributor to our knowledge of the thyroid gland and the role of thyroid hormone on brain development and one of the founding members of the European Thyroid Association and of the Hormones and Cell Regulation Symposium, died in Washington in February 2018. French, he was born in Tunis (Tunisia) in 1927 in a Jewish family of Italian origin. He began his career as a fundamental organic chemist at the Pasteur Institute, then ,as biochemist, at the College of France, Inserm and finally at the NIH.The first part of his career was devoted to the biosynthesis of thyroid hormone and the control of thyroid cell metabolism.  In particular he discovered reverse T3, characterized the enzymatic systems (thyroperoxidase  ,H2O2 generating system etc.,) involved in the synthesis of thyroid hormones. He also developed the field of the biochemical actions of thyroid hormones. He then began a major research activity on the role of microtubules and microtubule-associated proteins on brain development and on their regulation by thyroid hormones. He described the changes in activity and composition of the microtubule-associated proteins tau and MAP2 during brain development. 
During his stay in Bruxelles in 1982-1984, working with J.P. Brion, they discovered that tau proteins were the molecular component of neurofibrillary tangles, a key brain lesion in Alzheimer’s disease. This major discovery led him later to further findings in brain development and in Alzheimer’s disease.A major, authoritative figure in thyroid and in neurosciences, a forceful debater and organiser.
Nunez will be much regretted.

J E DUMONT , J P BRION   Francon J, Fellous A, Lennon AM, Nunez J: Is thyroxine a regulatory signal for neurotubule assembly during brain development? Nature 1977, 266:188-90. PMID 859595 Mareck A, Fellous A, Francon J, Nunez J: Changes in composition and activity of microtubule-associated proteins during brain development. Nature 1980, 284:353-5. PMID 7360270 Brion JP, Passareiro H, Nunez J, Flament-Durand J: Mise en évidence immunologique de la protéine tau au niveau des lésions de dégénérescence neurofibrillaire de la maladie d'Alzheimer. ArchBiol(Brux) 1985, 95:229-35.

Année
Organisateurs
Sujet
1976 J. Nunez
1977 J.E. Dumont
1978 H. Vandermolen
1979 J. Nunez
1980 Jeanrenaud
1981 Schultz
1982 Denton
1983 J.E. Dumont
1984 Hamprecht
1985 King
1986 J.E. Dumont
1987 Carafoli
1988 Denton
1989 J.E. Dumont
1990 King
1991 Hamprecht
1992 Cook
1993 Chambaz
1994 F. Hofmann
1995 Pinna
1996 Irvine
1997 J. Hanoune Cyclic AMP
1998 J.E. Dumont Control of cell proliferation
1999 Gröner Control of transcription
2000 S. Gammemtoft Protein kinase
2001 M. Parker Nuclear receptors
2002 J. Bockaert GPCRs and G proteins
2003 R. Marais Protein kinases in health & disease
2004 P. Gierschik Functional genomics of signal transduction
2005 M. Jäättelä Apoptosis
2006 R. Marais Cell Signalling in cancer
2007 M. Freismuth GPCR complexes and GPCR complexity
2008 G. Vecchio Molecular and cellular biology of endocrine cancers
2009 S. Schurmans, B. Payrastre Inositol & Phosphatases in Cell Signalling
2010 Carling Metabolism in physiology & Disease
2011 Clauser, Offermanns GPCRs
2012 P. Demeyts Receptor Tyrosine Kinases
2013 R. Di Lauro Development Disease Endocrine Organs
2014 B. Payrastre, S. Schurmans, C.Erneux Inositol Lipid Signalling
2015 M. Sibilia, D. Carling Hormones Cancer Metabolism
2016 J-P. Pin, S. Offermanns GPCR
2017 V. Flockerzi, T. Gudermann, U. Boehm Channels ionic Controls
2018 P. Demeyts The brain – gut – microbiome network in metabolic regulation and dysregulation.
2019 B. Payrastre, S. Schurmans, C.Erneux
Inositol LIPIDS in health and diseases
2020 I. Huhtaniemi, A. Maggi
Sex and Signaling: the molecular basis of sex and gender medicine