Welcome to

43rd Symposium on Hormones and Cell Regulation


The brain – gut – microbiome network in metabolic regulation and dysregulation



Mont Ste Odile (France)
10-13 October  2018




Invited speakers :


Emrah Altindis, USA

Ellen Blaak, The Netherlands

Tristan Bolmont, Switzerland

Patrizia Brigidi, Italy

Remy Burcelin, France.

Filipe Cabreiro, UK

Sylvie Claeysen, France

Karine Clément, France

John Cryan, Ireland

Nathalie Delzenne, Belgium

Joël Doré, France

Eran Elinav, Israel

Amandine Everard, Belgium

Colin Hill, Ireland

Jens Juul Holst, Denmark

Ruth Ley, Germany.

Gilles Mithieux, France

Max Nieuwdorp, The Netherlands

Louise Oloffson, Sweden.

Vassilis Pachnis, UK

Oluf B. Pedersen, Denmark

Jarrad M. Scarlett, USA

Marion Soto, France

Bart Staels, France

Herbert Tilg, Austria

Siegfried Ussar, Germany

Hubert Vidal, France.

Helen Vuong, USA





The very nature of endocrinology has undergone major paradigm shifts over the last  few decades with the discovery of endocrine functions by organs not hitherto considered as endocrine organs, such as fat, the gut and the brain, both as metabolism regulators and targets of regulation through organ crosstalk. In addition, a major conceptual revolution has taken place in the last few years with the explosion of interest in the role of the symbiosis between animals and the microbes they host, primarily in the gut (microbiome), in metabolic regulation. This symposium will attempt to paint a coherent picture of the interactions between the brain, the gut and the microbiome as a crucial network involved in metabolic regulation as well as its disturbances in obesity, type 2 diabetes and neurodegenerative disorders. We bring leading investigators in the field together with established scientists, postdocs and students in a convivial and highly interactive environment in a historical and inspiring setup.


  1. Cross-talk between the brain and the gut in metabolic regulation.
  1. The gut microbiota: a complex ecosystem and its interaction with host cells.
  1. New mediators/targets in gut function.
  1. The gut microbiome in metabolic regulation and dysregulation across lifespan.
  1. The gut microbiome and CNS dysfunction
  1. Therapeutic perspectives


For any contact with the organization of the Congress in 2018, only use the following email address
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Where? The Mont Sainte-Odile (30 km from Strasbourg), an old abbey founded more than 13 centuries ago in Alsace, France


Program ?  PROGRAMME

When? Wednesday,  10 OCTOBER   to Saturday, 13 OCTOBER  2018



Some pictures of ottrott and mont Saint-Odile :   Colour gallery   and   B/W gallery



Practical information :


The symposium starts on Wednesday 10 October  at 3 pm


There is a bus coming to Strasbourg airport on Wednesday, 10 October at 11:25h, picking up the participants landing from 10am - 11:25am;

another bus is driving to Strasbourg main station at 1:30pm picking up the participants coming between 11am and 1:30pm.


A snack will be served at Mont Ste Odile at 2 pm
before the beginning of the conferences.

Departure is scheduled on Saturday 13 October . The bus will leave Mont Ste Odile at 2 pm after lunch and
will arrive at the airport at 2:45 pm and at the railroad station at 3:30 pm


If you cannot make the bus, a taxi from Strasbourg costs around 90 euros. Alternatively, there are trains from Strasbourg to Obernai (TER line Strasbourg-Molsheim-Obernai-Barr-Sélestat) every 30 min starting at 15h40.

Not all trains stop at the airport, but you can manage to go to Molsheim and

board the next train to Obernai.

A list of taxis in Obernai is here

Abstract and Poster information :


Uploading abstracts: Abstracts can be uploaded using the template available during the online registration process. 

You will also be able to upload your abstract following your registration by logging back in using the username and password which you will have received on registration;

the abstract template will be available for you to download.


The panel size for posters is 2m high and 80 cm wide.




        Nunez a major contributor to our knowledge of the thyroid gland and the role of thyroid hormone on brain development and one of the founding members of the European Thyroid Association and of the Hormones and Cell Regulation Symposium, died in Washington in February 2018.

French, he was born in Tunis (Tunisia) in 1927 in a Jewish family of Italian origin. He began his career as a fundamental organic chemist at the Pasteur Institute, then ,as biochemist, at the College of France, Inserm and finally at the NIH.

The first part of his career was devoted to the biosynthesis of thyroid hormone and the control of thyroid cell metabolism. In particular he discovered reverse T3, characterized the enzymatic systems (thyroperoxidase  ,H2O2 generating system etc.,) involved in the synthesis of thyroid hormones. He also developed the field of the biochemical actions of thyroid hormones. He then began a major research activity on the role of microtubules and microtubule-associated proteins on brain development and on their regulation by thyroid hormones. He described the changes in activity and composition of the microtubule-associated proteins tau and MAP2 during brain development. During his stay in Bruxelles in 1982-1984, working with J.P. Brion, they discovered that tau proteins were the molecular component of neurofibrillary tangles, a key brain lesion in Alzheimer’s disease. This major discovery led him later to further findings in brain development and in Alzheimer’s disease.

A major, authoritative figure in thyroid and in neurosciences, a forceful debater and organiser.

  1. Nunez will be much regretted.





Francon J, Fellous A, Lennon AM, Nunez J: Is thyroxine a regulatory signal for neurotubule assembly during brain development? Nature 1977, 266:188-90. PMID 859595


Mareck A, Fellous A, Francon J, Nunez J: Changes in composition and activity of microtubule-associated proteins during brain development. Nature 1980, 284:353-5. PMID 7360270


Brion JP, Passareiro H, Nunez J, Flament-Durand J: Mise en évidence immunologique de la protéine tau au niveau des lésions de dégénérescence neurofibrillaire de la maladie d'Alzheimer. ArchBiol(Brux) 1985, 95:229-35.



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